A drug that provides the benefits obtained from medicinal cannabis without the “high” or other side effects may help to unlock a new treatment for Parkinson’s disease.
The drug — HU-308 — lessens devastating involuntary movements called dyskinesias, a side effect from years of treatment for Parkinson’s disease.
The research, published today in Neurobiology of Disease, has been conducted by the Centre for Neuroscience and Regenerative Medicine (CNRM) at the University of Technology Sydney (UTS) and the Applied Medical Research Institute of St Vincent’s Hospital Sydney.
The study shows that in mice HU-308 is as effective as amantadine, the only available treatment for dyskinesias. Furthermore, the combination of HU-308 with amantadine is more effective than either drug used alone.